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Are you Made for life-saving breakthroughs?

We’ll give you the opportunity to make them happen. As leaders in Bioelectronic Medicine, immunology, neuroscience, cardiopulmonology, oncology, psychiatric disorders and the molecular genetics of disease, we’re passionate about discovering and applying innovative new treatments and therapies to make this a healthier world.

Feinstein Institute for Medical Research

With 12 Centers of Excellence and 55 labs – and growing – the Feinstein Institute for Medical Research conducts cutting-edge work in major diseases, from cancer to lupus to sepsis. We are also a world leader in bioelectronic medicine. By combining neuroscience, molecular biology, and bioengineering, we’re achieving incredible breakthroughs in the treatment of rheumatoid arthritis, Crohn’s disease, hemorrhaging and more.

At the Feinstein Institute, our emphasis is on translational research – taking treatments from the lab to the bedside as directly and quickly as possible. Being at the heart of a vast, demographically-diverse patient population puts us on the front lines of modern medical treatment.

It also means that we are a partner of choice for medical industry leaders, including prominent pharmaceutical, device engineering, and biochemical enterprises. We provide our partners with research excellence and the ability to run clinical trials in a demographically-rich patient population.

We rank among the nation’s leaders in terms of NIH grants per researcher. Every year, more than 15,000 patients participate in over 2,000 research studies.

Join us for a career where medical research and technology meet on the road to making new discoveries that cure diseases.

Our Careers include opportunities in the fields of:

Preclinical laboratory science
Translational science
Health outcomes research
Behavioral science
Biostatistics and data analytics
Administration

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Employee Stories, Research

From Assistant Clinical Analyst to AVP of the Office of Research Compliance – my career journey

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Aug 31, 2017

Since joining our team in 2005, Emmelyn has taken every challenge and turned it into an opportunity. Learn how her career progressed over the years and how we supported her along her journey.

Research

We’re sending shock waves throughout the medical world.

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Jun 09, 2017

Bioelectronic Medicine combines our knowledge of electrical signals and neural pathways to redefine how we predict, diagnose, and treat an incredible range of medical conditions. We’re teaching the body how to heal itself – without side effects. Learn more.

Research

Unleashing the Power of Bioelectronic Medicine.

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Apr 04, 2017

Are you ready to work on the leading edge of one of the most exciting areas of medical research today? Bioelectronic Medicine is revolutionizing health care by replacing drugs with electrons – using devices to guide nerves to control molecular targets. The possibilities for changing and saving lives are limitless.

Employee Stories, Research

Turning a dream into reality - the birth of 3D bioprinting

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Feb 01, 2017

Years ago Todd Goldstein never thought he would be able to make his 3D bioprinting innovation a reality, but with the support of Northwell Health and a few mentors he was able to win our 2016 Medical Innovation Contest. Read more about his journey.

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Our research center leaders

The Feinstein Institute is comprised of 12 centers of excellence with more than 55 research programs, meet our leaders:

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Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases

Led by Betty Diamond, MD

The immune system is a complex set of cells and tissues that protect the body from invaders such as viruses or bacteria. Sometimes, however, this system goes awry and mistakes its own cells as invaders and repeatedly attacks them — this is called autoimmunity. Researchers in the Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases focus on major types of autoimmune diseases, including arthritis, lupus, hearing disorders, multiple sclerosis, spinal cord injury and disc degeneration. They extensively research the function of risk genes and the mechanisms of tissue injury and develop novel therapies to treat them.

Center for Immunology and Inflammation

Led by Ping Wang, MD

Researchers in the Center for Immunology and Inflammation focus on understanding the basic biological principles of the immune system that protect the body against infections, environmental hazards and internal challenges, and how this system is impaired in disease. They carry out basic, translational and patient-oriented research on a range of immune and inflammatory disorders, including sepsis, allergy and hypersensitivity, kidney injury, cancer, immune deficiency, HIV infection and conditions affecting maternal, fetal and neonatal health. Their ultimate goal is to develop improved treatments for these life-threatening conditions.

Feinstein Center for Neurosciences

Led by David Eidelberg, MD

The mission of the Center for Neurosciences is to shed light on the abnormalities of functional brain organization that underlie nervous system disease.

To characterize these networks as biomarkers of disease and treatment, investigators use multimodal brain imaging in conjunction with novel computational methods. Study populations include healthy volunteers and patients with Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, dystonia and Tourette syndrome.

Center for Bioelectronic Medicine

Led by Yousef Al-Abed, PHD

Bioelectronic medicine is an emerging field of medicine that combines neuroscience, molecular biology and bioengineering to tap into the nervous system to treat disease and injury without the use of pharmaceuticals. Researchers in the Center study the nervous system at the molecular level to understand how it interacts with the brain and organs. Using advanced technology, they listen to the neural signals sent along the body’s enervated pathways to regulate disease and injury, and produce highly targeted treatments. Conditions identified as benefiting from bioelectronic medicine therapies include rheumatoid arthritis, Crohn’s disease, diabetes, paralysis and lupus.

Center for Molecular Innovation

Led by Yousef Al-Abed, PHD

The Center for Molecular Innovation leads the discovery and development of novel therapeutics, improving the lives of patients suffering from a variety of conditions including lupus, arthritis, diabetes, sepsis and Alzheimer’s disease. It integrates innovative approaches in target discovery with medicinal chemistry to generate small organic compounds and potential drugs. The center’s discoveries have identified several drug candidates and uncovered existing drugs that could be repurposed to target critical proteins involved in neurodegenerative and autoimmune diseases.

Karches Center for Oncology Research

Led by Nicholas Chiorazzi, MD

Researchers in the Karches Center for Oncology Research study cancer and related aspects of cell biology, all geared toward understanding the abnormal growth and behavior of cells that have been malignantly transformed. This information is used to develop and test new diagnostics and treatments for patients suffering from several types of cancers.

Center for Biomedical Science

Led by Kevin J. Tracey, MD

Researchers in the Center for Biomedical Science are a diverse group of scientists, physicians, and engineers who study the dynamic interface of the nervous system and the immune system. They discovered the inflammatory reflex – a neural circuit in which the brain controls the immune system. Building on this discovery, they study the molecular basis of inflammation, as well as the physiology and molecular biology of neural circuits in different organ systems. These studies are forming a foundation of knowledge that may be used to develop new drugs and devices that modulate nerves to cure disease.

Center for Pediatric Research

Led by Charles Schleien, MD

The goal of the Center for Pediatric Research is to explore the diseases and conditions that affect children and adolescents, to examine the conditions under which they occur, and to identify the barriers that limit provision of the highest quality care to all children. To achieve this goal, researchers in the Center conduct basic and translational investigation, including clinical trials, and examine the manner in which health care to children and their families is delivered and financed.

Litwin-Zucker Center for Alzheimer’s Disease and Memory Disorders

Led by Peter Davies, PHD

The Litwin-Zucker Center for Alzheimer’s Disease and Memory Disorders is the only dedicated Alzheimer’s disease research facility on Long Island. Those in the center are committed to identifying new ways to detect and treat Alzheimer’s disease. This effort is critical not only to our local community, but to the population overall — as a result of the aging population and increased life expectancy, the number of Americans age 65 and older with Alzheimer’s disease may nearly triple by 2050.

Center for Health Innovations and Outcomes Research

Led by Thomas McGinn, MD

The Center for Health Innovations and Outcomes Research leverages Big Data and incorporates cutting-edge technologies to deliver innovative health care solutions to improve how we deliver care. Researchers utilize mixed methodologies and the latest data analytic tools to develop interventions and assess outcomes related to a wide variety of medical conditions. Drawing on the expertise of a multidisciplinary team that includes physicians, psychologists, economists, IT programmers, biostatisticians, and public health professionals, the Center’s researchers are collaborating across specialties and clinical settings to identify innovative solutions to today’s pressing health care issues.

Center for Psychiatric Neuroscience

Led by John M. Kane, MD

The mission of the Center for Psychiatric Neuroscience is to study behavioral health to identify causes, triggers, markers and treatments for such illnesses as bipolar disorder, schizophrenia and other psychotic disorders.

Combining different perspectives in multi-disciplinary research is key to making advances in these illnesses. The Feinstein Institute and the Zucker Hillside Hospital provide valuable platforms to advance such efforts.

Robert S. Boas Center for Genomics and Human Genetics

Led by Peter K. Gregersen, MD

The mission of the Robert S. Boas Center for Genomics and Human Genetics is to identify and understand the genetic contribution to human diseases and translate these discoveries into new diagnostics and therapeutics. Center researchers are focused on autoimmune diseases and neuropsychiatric traits and disorders, and conduct a full range of human genetics research.

Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases

Led by Betty Diamond, MD

The immune system is a complex set of cells and tissues that protect the body from invaders such as viruses or bacteria. Sometimes, however, this system goes awry and mistakes its own cells as invaders and repeatedly attacks them — this is called autoimmunity. Researchers in the Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases focus on major types of autoimmune diseases, including arthritis, lupus, hearing disorders, multiple sclerosis, spinal cord injury and disc degeneration. They extensively research the function of risk genes and the mechanisms of tissue injury and develop novel therapies to treat them.

Center for Bioelectronic Medicine

Led by Yousef Al-Abed, PHD

Bioelectronic medicine is an emerging field of medicine that combines neuroscience, molecular biology and bioengineering to tap into the nervous system to treat disease and injury without the use of pharmaceuticals. Researchers in the Center study the nervous system at the molecular level to understand how it interacts with the brain and organs. Using advanced technology, they listen to the neural signals sent along the body’s enervated pathways to regulate disease and injury, and produce highly targeted treatments. Conditions identified as benefiting from bioelectronic medicine therapies include rheumatoid arthritis, Crohn’s disease, diabetes, paralysis and lupus.

Center for Biomedical Science

Led by Kevin J. Tracey, MD

Researchers in the Center for Biomedical Science are a diverse group of scientists, physicians, and engineers who study the dynamic interface of the nervous system and the immune system. They discovered the inflammatory reflex – a neural circuit in which the brain controls the immune system. Building on this discovery, they study the molecular basis of inflammation, as well as the physiology and molecular biology of neural circuits in different organ systems. These studies are forming a foundation of knowledge that may be used to develop new drugs and devices that modulate nerves to cure disease.

Center for Health Innovations and Outcomes Research

Led by Thomas McGinn, MD

The Center for Health Innovations and Outcomes Research leverages Big Data and incorporates cutting-edge technologies to deliver innovative health care solutions to improve how we deliver care. Researchers utilize mixed methodologies and the latest data analytic tools to develop interventions and assess outcomes related to a wide variety of medical conditions. Drawing on the expertise of a multidisciplinary team that includes physicians, psychologists, economists, IT programmers, biostatisticians, and public health professionals, the Center’s researchers are collaborating across specialties and clinical settings to identify innovative solutions to today’s pressing health care issues.

Center for Immunology and Inflammation

Led by Ping Wang, MD

Researchers in the Center for Immunology and Inflammation focus on understanding the basic biological principles of the immune system that protect the body against infections, environmental hazards and internal challenges, and how this system is impaired in disease. They carry out basic, translational and patient-oriented research on a range of immune and inflammatory disorders, including sepsis, allergy and hypersensitivity, kidney injury, cancer, immune deficiency, HIV infection and conditions affecting maternal, fetal and neonatal health. Their ultimate goal is to develop improved treatments for these life-threatening conditions.

Center for Molecular Innovation

Led by Yousef Al-Abed, PHD

The Center for Molecular Innovation leads the discovery and development of novel therapeutics, improving the lives of patients suffering from a variety of conditions including lupus, arthritis, diabetes, sepsis and Alzheimer’s disease. It integrates innovative approaches in target discovery with medicinal chemistry to generate small organic compounds and potential drugs. The center’s discoveries have identified several drug candidates and uncovered existing drugs that could be repurposed to target critical proteins involved in neurodegenerative and autoimmune diseases.

Center for Pediatric Research

Led by Charles Schleien, MD

The goal of the Center for Pediatric Research is to explore the diseases and conditions that affect children and adolescents, to examine the conditions under which they occur, and to identify the barriers that limit provision of the highest quality care to all children. To achieve this goal, researchers in the Center conduct basic and translational investigation, including clinical trials, and examine the manner in which health care to children and their families is delivered and financed.

Center for Psychiatric Neuroscience

Led by John M. Kane, MD

The mission of the Center for Psychiatric Neuroscience is to study behavioral health to identify causes, triggers, markers and treatments for such illnesses as bipolar disorder, schizophrenia and other psychotic disorders.

Combining different perspectives in multi-disciplinary research is key to making advances in these illnesses. The Feinstein Institute and the Zucker Hillside Hospital provide valuable platforms to advance such efforts.

Feinstein Center for Neurosciences

Led by David Eidelberg, MD

The mission of the Center for Neurosciences is to shed light on the abnormalities of functional brain organization that underlie nervous system disease.

To characterize these networks as biomarkers of disease and treatment, investigators use multimodal brain imaging in conjunction with novel computational methods. Study populations include healthy volunteers and patients with Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, dystonia and Tourette syndrome.

Karches Center for Oncology Research

Led by Nicholas Chiorazzi, MD

Researchers in the Karches Center for Oncology Research study cancer and related aspects of cell biology, all geared toward understanding the abnormal growth and behavior of cells that have been malignantly transformed. This information is used to develop and test new diagnostics and treatments for patients suffering from several types of cancers.

Litwin-Zucker Center for Alzheimer’s Disease and Memory Disorders

Led by Peter Davies, PHD

The Litwin-Zucker Center for Alzheimer’s Disease and Memory Disorders is the only dedicated Alzheimer’s disease research facility on Long Island. Those in the center are committed to identifying new ways to detect and treat Alzheimer’s disease. This effort is critical not only to our local community, but to the population overall — as a result of the aging population and increased life expectancy, the number of Americans age 65 and older with Alzheimer’s disease may nearly triple by 2050.

Robert S. Boas Center for Genomics and Human Genetics

Led by Peter K. Gregersen, MD

The mission of the Robert S. Boas Center for Genomics and Human Genetics is to identify and understand the genetic contribution to human diseases and translate these discoveries into new diagnostics and therapeutics. Center researchers are focused on autoimmune diseases and neuropsychiatric traits and disorders, and conduct a full range of human genetics research.

Did you know?

2017 was an exciting year for us, putting us in a great position to take on important new clinical research challenges:

The Feinstein Institute received more than $150M in new financial commitments

Eighteen Feinstein Institute researchers were awarded grants over $1M

Grant submissions increased 43% from 2015

National Institutes of Health (NIH) funding increased 19% from 2016

Feinstein Institute staff ranked third in NIH funding per investigator – $893,705 per investigator

The Feinstein Institute ranked in the top 7.7% for total NIH funding

The Feinstein Institute received more than $150M in new financial commitments

Eighteen Feinstein Institute researchers were awarded grants over $1M

Grant submissions increased 43% from 2015

National Institutes of Health (NIH) funding increased 19% from 2016

Feinstein Institute staff ranked third in NIH funding per investigator – $893,705 per investigator

The Feinstein Institute ranked in the top 7.7% for total NIH funding

The Feinstein Institute received more than $150M in new financial commitments

Eighteen Feinstein Institute researchers were awarded grants over $1M

Grant submissions increased 43% from 2015

National Institutes of Health (NIH) funding increased 19% from 2016

Feinstein Institute staff ranked third in NIH funding per investigator – $893,705 per investigator

The Feinstein Institute ranked in the top 7.7% for total NIH funding

The Feinstein Institute received more than $150M in new financial commitments

Eighteen Feinstein Institute researchers were awarded grants over $1M

Grant submissions increased 43% from 2015

National Institutes of Health (NIH) funding increased 19% from 2016

Feinstein Institute staff ranked third in NIH funding per investigator – $893,705 per investigator

The Feinstein Institute ranked in the top 7.7% for total NIH funding

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In 2017, our researchers published 1,723 scientific and clinical research papers in the world’s leading journals, including:

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The national academy of sciences in service to the nation

Theodoros Zanos, PhD, Harold Silverman, PhD and Kevin Tracey, MD, and their colleagues were the first to decode specific vagus nerve signals used to communicate immune status and inflammation to the brain, published in Proceedings of the National Academy of Sciences (PNAS).

Sangeeta S. Chavan, PhD, Valentin A. Pavlov, PhD, and Kevin J. Tracey, MD, reviewed the connections between the nervous and immune systems to facilitate development of bioelectronic devices as published in Immunity.

Amrit Chiluwal, MD, Raj K. Narayan, MD, Wayne Chaung, PhD, Neal Mehan, MD, Ping Wang, MD, Chad Bouton, and Chunyan Li, PhD, found that trigeminal nerve stimulation (TNS) resulted in increased cerebral blood flow and oxygen to the brain in mice with a severe traumatic brain injury as published in Scientific Reports.

Christoph Correll, MD, and his team summarized the efficacy of antipsychotic drug combination strategies in adults with schizophrenia as published in JAMA Psychiatry.

Kristina M. Deligiannidis, MD, and colleagues studied a new drug to reduce symptoms in severe postpartum depression (PDD) as published in The Lancet.

Valentin A. Pavlov, PhD, and Fernanda Consolim-Colombo, MD, PhD, from the University of Sao Paulo, Brazil lead a team of colleagues who discovered that the FDA-approved Alzheimer’s drug “galantamine” cut key markers of inflammation – a hallmark of metabolic syndrome – by more than 25% in obesity, leading to reduced insulin resistance as published in JCI Insight.

Harold A. Silverman, PhD, Sangeeta S. Chavan, PhD, and their colleagues standardized an experimental protocol to record signals transmitted in the vagus nerve, expanding our knowledge of the communication of inflammation to the brain, which can be used in the study of bioelectronic medicine and the development of bioelectronic medicine devices as published in Bioelectronic Medicine.

Gerin Rachel Stevens, MD, Daniel W. Ross, MD, along with colleagues reported their results on the impact of a popular pre-heart transplant therapy, the left ventricular assist device (LVAD), on the kidney as published in The Clinical Journal of the American Society of Nephrology.

Advanced technology to treat disease and injury

Bioelectronic Medicine (BEM) is one of the most exciting areas of medical research today and the Feinstein Institute for Medical Research is leading the way!

Unleash the limitless life-changing potential of Bioelectronic Medicine

Sponsorship programs and partnerships

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The Feinstein Institute for Medical Research has several programs and partnerships to help us study, test and improve our clinical breakthroughs. These include:

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Peter Davies, PhD, partnered with the Bristal at Lake Success to study the effects of dance therapy on memory  care patients.

John M. Kane, MD, enacted a collaboration agreement with IBM to identify and extract features from social media that predict psychotic and/or depressive tendencies.

Peter K. Gregerson, MD, provided genotype services to Genetech, Inc.

In 2017, the Feinstein Institute received more than $150M in new financial commitments from federal and state agencies, strategic partners, Northwell Health, and philanthropic benefactors. Eighteen Feinstein Institute researchers were awarded grants over $1M.

$Kevin J. Tracey, MD, received a $5.7M grant from United Therapeutics Corp. to develop an engineered autologous cell therapy to treat refractory hypertension.$

The Center for Bioelectronic Medicine received $3.9 million  in joint research support from United Therapeutics Corp. to develop breakthrough therapy  to resolve or reduce pulmonary arterial hypertension.

Lance Becker, MD, received a $2.4M grant from the United Therapeutics Corp. to study therapeutic improvements to prolong windows of donations after circulatory death.

Jacqueline Moline, MD, received a $2.1M award from the Center for Disease Control and Prevention (CDC) to aid with operations, member services and case management components for the Queens World Trade Center Health Program at North Shore University Hospital.

Advancing Women in Science and Medicine (AWSM) distributed more than $225,000 in awards to top female Feinstein Institute scientists during its sixth annual luncheon. Since its inception, the Feinstein Institute has raised $1 million.

The Center for New Cancer Therapies is a phase I cancer clinical trials program, launched at the Monter Cancer Center in the Northwell Cancer Institute,  under medical director Robert Maki, MD, PhD, and associate director  Priscila Gonçalves, MD. It is opening up exciting new cancer therapy options, including immunotherapy agents, chemotherapy drugs and novel devices.